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Studies designed to provide insight into clinical practice in the real world are known as pragmatic trials. They are often focused on the practical aspects of the study design, including recruitment and consent as well as adherence to the use of standard equipment.

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Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which used different investigators and had participants from different geographic areas. This type of heterogeneity which is vital for a pragmatic trial to be reliable and to reduce bias in the results, 프라그마틱 슬롯체험 is also necessary. However too much heterogeneity could lead to issues with the design of the trial.

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Pragmatic trials seek to replicate real-life situations and attain maximum external validity. They are usually commissioned by policy makers and practitioners to guide their decision-making. They can also be used to assess the cause-effect relationship of an intervention and its results. However, they should not be used to substitute for the use of explanation trials.

The pragmatism idea is controversial, and there are doubts about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which prove the clinical or physiological hypothesis as well as pragmatic trials that inform policy and practice decisions. They also proposed a framework for pragmatic trials, dubbed PRECIS.2 This tool sought to define the elements of a practical trial, including the recruitment process, the design and delivery of the intervention, as well as the follow-up.

There is a growing increase in the number of pragmatic trials that have been published. A recent Medline search using the keywords pragmatic and naturalistic, restricted to controlled trials randomized to control (RCTs) resulted in 34 articles, shown in red in Figure 2. This is a sign that the health sciences community is becoming more acquaint to the issue of pragmatic thinking. It is important to remember that the majority of these studies were conducted in primary care settings.