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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are often characterized as a focus on the practical aspects of designing a study, including the recruitment process and consent, adhering and the use of standard equipment.

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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which used a variety of investigators and included participants from various geographical areas. This type of heterogeneity which is essential for a pragmatic trial to be valid and lessen the chance of bias is also essential. However, too much heterogeneity can cause issues with the design of the trial.

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The goal of pragmatic trials is to mimic real-life scenarios and to achieve maximum credibility externally. They are usually requested by policy makers and practitioners to inform their decision making. They can also be a great method to determine the causal relationship between the intervention and its effects. However, 무료슬롯 프라그마틱 they should not be used in lieu for 프라그마틱 데모 the use of explanation trials.

The concept of pragmatism is controversial and there are concerns about whether pragmatic trials should replace tests for explanations or if they should be an alternative to them. Schwartz and Lellouch1 suggested the distinction between explanation studies, which confirm the validity of a physiological or clinical hypothesis, and pragmatic trials, 프라그마틱 that inform policy and practice decision-making. They also proposed a framework called PRECIS for pragmatic trials.2 This tool tried to define the traits of a pragmatic study, including recruitment, design, delivery of the intervention and follow-up.

There is a growing trend in the number of pragmatic trials published. A recent Medline query that used the words pragmatic and naturalistic, which was restricted to randomised controlled trials (RCTs), returned 34 articles. These are shown in red on Figure 2. This indicates that the health sciences community has become more aware of the importance of pragmatic thinking. It is important to note, however, that the majority of studies were conducted in primary-care settings.