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Pragmatic trials are studies designed to inform the practice of clinical trials in real life. They are typically described as focusing on practical aspects of designing a study which include the recruitment and consent process, as well as adherence and the use routinely available equipment.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which employed a variety of investigators and included participants from different geographical regions. This type of heterogeneity is necessary for pragmatic trials to be valid and also reduces bias in the results. However excessive heterogeneity could cause problems with the design of the trial.

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The goal of pragmatic trials is to mimic real-life situations and achieve the highest level of validity externally. Usually, they are ordered by policymakers and practitioners to help inform their decisions. They can also be used to determine the causality of an intervention and its results. However, they should not be used to substitute for explanation studies.

The pragmatism idea is controversial, and there are concerns about whether pragmatic trials should be used to replace explanatory trials or 프라그마틱 카지노 complement them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which validate a physiological or clinical hypothesis as well as pragmatic trials that inform the practice and policy decisions. They also proposed the framework for pragmatic trials, called PRECIS.2 This tool sought to define the elements of a pragmatic trial, including the recruitment process, the design and implementation of the intervention, 프라그마틱 슬롯 하는법 슬롯 환수율 (Bookmarkcork.Com) as well as follow-up.

There is a positive trend in the number of pragmatic trials published. A recent Medline search using the words pragmatic and naturalistic, which was restricted to randomised controlled trials (RCTs), returned 34 articles. These are highlighted in red on Figure 2. This is an indication that the health sciences community is becoming more sensitive to the subject of pragmatic thinking. It is important to note, however, that the majority of these studies were conducted in primary-care settings.